TB-500
Synthetic peptide studied in animal and cell models for universal tissue repair and anti-inflammatory action
Last updated: March 1, 2026
- Compound
- TB-500
- Class
- Recovery peptide
- Summary
- Synthetic peptide studied in animal and cell models for universal tissue repair, anti-inflammatory action, reduced scar formation.
- Mechanism
- Organized Tissue Remodeling
- Research Status
- Preclinical
- Routes Studied
- Subcutaneous injection
- Evidence Level
- Preclinical-promising · Clinically unproven
What Should You Know About TB-500?
- What is TB-500?
- TB-500 is a synthetic peptide studied in animal and cell models for universal tissue repair and potent anti-inflammatory action.
- Is TB-500 clinically proven?
- No. Human evidence remains limited and does not establish TB-500 as clinically proven.
- What has TB-500 been studied for?
- TB-500 has been studied in preclinical models of universal tissue repair, potent anti-inflammatory action, reduced scar formation. These findings have not been confirmed in large-scale human trials.
- Is TB-500 approved?
- No. TB-500 is not an approved drug and remains a research compound.
What Is TB-500?
TB-500 is a synthetic version of the naturally occurring 43-amino acid peptide Thymosin Beta-4 (Tβ4), one of the most abundant intracellular proteins in mammalian tissue. First isolated from the thymus gland, the organ responsible for T-cell maturation and immune system development, Thymosin Beta-4 was initially studied for its immunological properties before its remarkable tissue repair capabilities were discovered. TB-500 replicates the active region of the full Thymosin Beta-4 protein, focusing...
Evidence Summary
TB-500 has extensive preclinical evidence (80+ PubMed citations) but no human clinical trial data. Most claims exceed current evidence.
Evidence Breakdown
| Domain | Evidence Level |
|---|---|
| Universal Tissue Repair | Animal studies |
| Anti-Inflammatory Action | Animal studies |
| Reduced Scar Formation | Animal studies |
| Angiogenesis | Animal studies |
| Human clinical evidence | Limited |
| Safety data | Insufficient |
Editorial Position
TB-500 is best understood as a preclinical research compound with promising biological signals but limited human validation. Many online claims exceed the strength of available human evidence, and safety data remains incomplete. Any consideration of this compound should involve careful evaluation of individual context and medical guidance.
Regulatory Status Snapshot
- Not approved as a therapeutic drug by major regulators
- Safety profile not established in large human populations
Need help interpreting this evidence for your situation?
Talk to a SpecialistA deep research review for TB-500 is not yet available. This compound profile is based on published peer-reviewed references listed below.
Browse all research reviewsWhat Has TB-500 Been Studied For?
Research areas where TB-500 has been investigated in published studies
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Universal Tissue Repair TB-500 has been studied in animal models of universal tissue repair. These findings have not been confirmed in controlled human trials.
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Anti-Inflammatory Action TB-500 has been studied in animal models of anti-inflammatory action. These findings have not been confirmed in controlled human trials.
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Reduced Scar Formation TB-500 has been studied in animal models of reduced scar formation. These findings have not been confirmed in controlled human trials.
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Angiogenesis TB-500 has been studied in animal models of angiogenesis. These findings have not been confirmed in controlled human trials.
How Does TB-500 Work?
These mechanisms have been observed in preclinical models. They are plausible but have not been linked to proven clinical outcomes in humans.
- 01 G-Actin Sequestration
- 02 Enhanced Cell Migration
- 03 Angiogenesis via Endothelial Migration
- 04 Anti-Inflammatory Cascade
Not sure if TB-500 is right for you?
A specialist can review the evidence, evaluate your medical context, and help you make an informed decision about TB-500.
Community Reports (Anecdotal)
Experiences shared here are self-reported and do not represent clinical evidence.
Rate TB-500
How Is TB-500 Administered?
TB-500 is available via Subcutaneous injection, auto-injector pen. Appropriate use and protocol should be determined by a qualified specialist.
What Are the Specifications of TB-500?
What Conditions Has TB-500 Been Linked To?
Have Questions About TB-500?
Published studies on TB-500 can be found on PubMed and other peer-reviewed databases. Our references section below lists key citations.
TB-500 is available as a research compound in Thailand. Consult a qualified specialist to discuss whether it is appropriate for your needs.
A qualified specialist experienced with peptide therapies can help you understand the current evidence and determine suitability.
Ready to discuss TB-500 with a specialist?
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Book a Consultation Free initial consultation. No obligation.Reviewed by the Peptide Science Thailand Editorial Team.
Last reviewed: March 1, 2026