AOD-9604
Synthetic peptide studied in animal and cell models for targeted lipolysis and no hormonal side effects
Last updated: March 1, 2026
- Compound
- AOD-9604
- Class
- Body Composition peptide
- Summary
- Synthetic peptide studied in animal and cell models for targeted lipolysis, no hormonal side effects, lipogenesis prevention.
- Mechanism
- No IGF-1 or Glucose Effects
- Research Status
- Phase II
- Routes Studied
- Subcutaneous injection
- Evidence Level
- Preclinical-promising · Clinically unproven
What Should You Know About AOD-9604?
- What is AOD-9604?
- AOD-9604 is a synthetic peptide studied in animal and cell models for lipolysis and no hormonal side effects.
- Is AOD-9604 clinically proven?
- No. Human evidence remains limited and does not establish AOD-9604 as clinically proven.
- What has AOD-9604 been studied for?
- AOD-9604 has been studied in preclinical models of lipolysis, no hormonal side effects, lipogenesis prevention. These findings have not been confirmed in large-scale human trials.
- Is AOD-9604 approved?
- No. AOD-9604 is not an approved drug and remains a research compound.
What Is AOD-9604?
AOD-9604 (Advanced Obesity Drug-9604) is a modified fragment of human growth hormone, specifically corresponding to amino acids 176-191 of the GH molecule with an additional N-terminal tyrosine residue. This fragment was identified and developed by Professor Frank Ng and colleagues at Monash University in Melbourne, Australia, based on the discovery that the fat-metabolizing properties of growth hormone reside in a specific region of the GH molecule distinct from the regions...
Evidence Summary
AOD-9604 is a research compound with promising biological signals but limited human validation. Most claims exceed current clinical evidence.
Evidence Breakdown
| Domain | Evidence Level |
|---|---|
| Targeted Lipolysis | Limited |
| No Hormonal Side Effects | Limited |
| Lipogenesis Prevention | Limited |
| FDA GRAS Safety Status | Limited |
| Human clinical evidence | Limited |
| Safety data | Insufficient |
Editorial Position
AOD-9604 is best understood as a compound with emerging clinical evidence that has not yet reached definitive conclusions. Many online claims exceed the strength of available human evidence, and safety data remains incomplete. Any consideration of this compound should involve careful evaluation of individual context and medical guidance.
Regulatory Status Snapshot
- Not approved as a therapeutic drug by major regulators
- Safety profile not established in large human populations
Need help interpreting this evidence for your situation?
Talk to a SpecialistA deep research review for AOD-9604 is not yet available. This compound profile is based on published peer-reviewed references listed below.
Browse all research reviewsWhat Has AOD-9604 Been Studied For?
Research areas where AOD-9604 has been investigated in published studies
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Targeted Lipolysis AOD-9604 has been studied in animal models of targeted lipolysis. These findings have not been confirmed in controlled human trials.
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No Hormonal Side Effects AOD-9604 has been studied in animal models of no hormonal side effects. These findings have not been confirmed in controlled human trials.
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Lipogenesis Prevention AOD-9604 has been studied in animal models of lipogenesis prevention. These findings have not been confirmed in controlled human trials.
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FDA GRAS Safety Status AOD-9604 has been studied in animal models of fda gras safety status. These findings have not been confirmed in controlled human trials.
How Does AOD-9604 Work?
These mechanisms have been observed in preclinical models. They are plausible but have not been linked to proven clinical outcomes in humans.
- 01 GH C-Terminal Mimicry
- 02 Hormone-Sensitive Lipase Activation
- 03 Lipogenesis Inhibition
- 04 Selective Fat Depot Action
Not sure if AOD-9604 is right for you?
A specialist can review the evidence, evaluate your medical context, and help you make an informed decision about AOD-9604.
Community Reports (Anecdotal)
Experiences shared here are self-reported and do not represent clinical evidence.
Rate AOD-9604
How Is AOD-9604 Administered?
AOD-9604 is available via Subcutaneous injection. Appropriate use and protocol should be determined by a qualified specialist.
What Are the Specifications of AOD-9604?
What Conditions Has AOD-9604 Been Linked To?
Have Questions About AOD-9604?
AOD-9604 is a fragment of growth hormone (amino acids 176-191 plus a stabilizing tyrosine), isolated specifically for GH's fat-metabolizing properties.
No. One of AOD-9604's key advantages over full growth hormone is that it does not affect blood glucose or insulin sensitivity. This has been confirmed in clinical studies published in the Journal of Endocrinology.
Emerging research has identified potential cartilage regeneration properties for AOD-9604, including effects on chondrocyte proliferation and cartilage matrix production. Studies presented at orthopedic research conferences suggest possible applications in osteoarthritis and cartilage repair.
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Book a Consultation Free initial consultation. No obligation.Reviewed by the Peptide Science Thailand Editorial Team.
Last reviewed: March 1, 2026