5-Amino-1MQ
Synthetic peptide studied in animal and cell models for cellular energy expenditure and nad+ biosynthesis support
Last updated: March 1, 2026
- Compound
- 5-Amino-1MQ
- Class
- Body Composition peptide
- Summary
- Synthetic peptide studied in animal and cell models for cellular energy expenditure, nad+ biosynthesis support, epigenetic metabolic regulation.
- Mechanism
- Metabolic Reprogramming of Adipose Tissue
- Research Status
- Preclinical
- Routes Studied
- Oral administration (capsule) or subcutaneous injection
- Evidence Level
- Preclinical-promising · Clinically unproven
What Should You Know About 5-Amino-1MQ?
- What is 5-Amino-1MQ?
- 5-Amino-1MQ is a synthetic peptide studied in animal and cell models for cellular energy expenditure and nad+ biosynthesis support.
- Is 5-Amino-1MQ clinically proven?
- No. Human evidence remains limited and does not establish 5-Amino-1MQ as clinically proven.
- What has 5-Amino-1MQ been studied for?
- 5-Amino-1MQ has been studied in preclinical models of cellular energy expenditure, nad+ biosynthesis support, epigenetic metabolic regulation. These findings have not been confirmed in large-scale human trials.
- Is 5-Amino-1MQ approved?
- No. 5-Amino-1MQ is not an approved drug and remains a research compound.
What Is 5-Amino-1MQ?
5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small molecule research compound that functions as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that plays a central regulatory role in cellular energy metabolism, adipogenesis, and epigenetic regulation. Unlike traditional peptides composed of amino acid chains, 5-Amino-1MQ is a quinolinium-based small molecule, included in research compound libraries alongside peptides due to its relevance to metabolic optimization and body composition research. The compound was...
Evidence Summary
5-Amino-1MQ has preliminary preclinical evidence only. Human clinical trial data is not available.
Evidence Breakdown
| Domain | Evidence Level |
|---|---|
| Cellular Energy Expenditure | Animal studies |
| NAD+ Biosynthesis Support | Animal studies |
| Epigenetic Metabolic Regulation | Animal studies |
| Non-Hormonal, Non-Stimulant Mechanism | Animal studies |
| Human clinical evidence | Limited |
| Safety data | Insufficient |
Editorial Position
5-Amino-1MQ is best understood as a preclinical research compound with promising biological signals but limited human validation. Many online claims exceed the strength of available human evidence, and safety data remains incomplete. Any consideration of this compound should involve careful evaluation of individual context and medical guidance.
Regulatory Status Snapshot
- Not approved as a therapeutic drug by major regulators
- Safety profile not established in large human populations
Need help interpreting this evidence for your situation?
Talk to a SpecialistA deep research review for 5-Amino-1MQ is not yet available. This compound profile is based on published peer-reviewed references listed below.
Browse all research reviewsWhat Has 5-Amino-1MQ Been Studied For?
Research areas where 5-Amino-1MQ has been investigated in published studies
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Cellular Energy Expenditure 5-Amino-1MQ has been studied in animal models of cellular energy expenditure. These findings have not been confirmed in controlled human trials.
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NAD+ Biosynthesis Support 5-Amino-1MQ has been studied in animal models of nad+ biosynthesis support. These findings have not been confirmed in controlled human trials.
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Epigenetic Metabolic Regulation 5-Amino-1MQ has been studied in animal models of epigenetic metabolic regulation. These findings have not been confirmed in controlled human trials.
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Non-Hormonal, Non-Stimulant Mechanism 5-Amino-1MQ has been studied in animal models of non-hormonal, non-stimulant mechanism. These findings have not been confirmed in controlled human trials.
How Does 5-Amino-1MQ Work?
These mechanisms have been observed in preclinical models. They are plausible but have not been linked to proven clinical outcomes in humans.
- 01 NNMT Active Site Binding
- 02 SAM Pool Preservation
- 03 NAD+ Salvage Pathway Enhancement
- 04 Physiological outcome
Not sure if 5-Amino-1MQ is right for you?
A specialist can review the evidence, evaluate your medical context, and help you make an informed decision about 5-Amino-1MQ.
Community Reports (Anecdotal)
Experiences shared here are self-reported and do not represent clinical evidence.
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How Is 5-Amino-1MQ Administered?
5-Amino-1MQ is available via Oral administration (capsule) or subcutaneous injection. Appropriate use and protocol should be determined by a qualified specialist.
What Are the Specifications of 5-Amino-1MQ?
What Conditions Has 5-Amino-1MQ Been Linked To?
Have Questions About 5-Amino-1MQ?
Based on preclinical research, 5-Amino-1MQ does not appear to affect food intake or function as a central nervous system stimulant. Its metabolic effects are mediated through enzyme inhibition at the cellular level, influencing energy expenditure and fat metabolism through NAD+...
Published studies on 5-Amino-1MQ can be found on PubMed and other peer-reviewed databases. Our references section below lists key citations.
5-Amino-1MQ is available as a research compound in Thailand. Consult a qualified specialist to discuss whether it is appropriate for your needs.
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Book a Consultation Free initial consultation. No obligation.Reviewed by the Peptide Science Thailand Editorial Team.
Last reviewed: March 1, 2026